Meet the Executive Leadership Team

Working to improve and help patients’ lives everywhere

Deborah C. Mash PhD

Chief Executive Officer and President

Deborah Mash is Professor of Neurology (Emeritus) and Molecular and Cellular Pharmacology at the University of Miami School of Medicine. She has held uninterrupted NIH funding from the National Institute on Drug Abuse for over twenty-five years. She is one of the world’s foremost scientific experts on the anti-addiction drug ibogaine and she is credited with the discovery of the active metabolite of ibogaine – Noribogaine. She first obtained clinical trial approval by the FDA in 1993 for an investigator initiated clinical Phase I safety and pharmacokinetic study of ibogaine in the USA. In 1996, she founded and directed Novoneuron Inc. to advance research and development of ibogaine and Noribogaine. From 1996-2005, she conducted offshore research and clinical development studies at a substance abuse treatment center in St. Kitts, WI to support medication development of ibogaine for opioid and other substance abuse disorders. In 2010, she founded DemeRx with Steve Gorlin to advance clinical development of the metabolite of ibogaine – Noribogaine. Deborah served as Director and Chief Scientific Officer at DemeRx, Inc. from 2010 to 2013. She took over the leadership of DemeRx at the end of July 2017, bringing together new management with strategic vision.

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Mark Ellison, PhD

President of Clinical Operations and Chief Development Officer

Mark Ellison has over 25 years of pharmaceutical experience with a track record of propelling start-ups & small pharma to maximize their capabilities in moving new products through the development process & bringing them to market. Mark was the Chief Development Officer at Opiant Pharmaceuticals who developed Narcan Nasal Spray a life changing product in the battle against opioid overdose, and Opvee (Nalmefene) Nasal Spray a product with the potential to tackle the fentanyl crisis. Prior to this he served as the Head of Technical Affairs at S.L.A. Pharma and held leadership and management positions at the Medicines and Healthcare Products Regulatory Agency (MHRA), Link Pharmaceuticals, DMV International and Merck.

E. Douglas Kramer, MD

Vice President, Clinical and Regulatory Affairs

Dr. Kramer obtained his medical degree from Columbia University and has more than 30 years of experience in drug development including regulatory affairs, pharmacovigilance, management, and domestic and international drug control and abuse liability evaluation. He has advanced the clinical development of addiction treatment medicines, opioid and non-opioid analgesics, and cancer chemotherapy in large and small pharmaceutical companies. Dr. Kramer has experience in all phases of development from pre-IND to Phase 3. He was previously a Medical Officer for the FDA Center for Drug Evaluation and Research Division of Anesthetic, Critical Care, and Addiction Drug Products. During his time with the FDA, he reviewed INDs and NDAs for analgesics in development (including NSAID, opioid, and combination products in both immediate-release and controlled-release dosage forms), the treatment of substance use disorders (including nicotine, opioid, stimulant dependence, and alcoholism) and requests for INDs for human administration of drugs of abuse.

John C. Thomas Jr., Treasurer

Chief Financial Officer and Secretary

John C. Thomas, Jr. has served as our Treasurer, Chief Financial Officer and Secretary since 2017, he previously held the Chief Financial Officer position at the Company from 2010 – 2013. Mr. Thomas also has served as Chief Financial Officer of the following companies founded by one of DemeRx’s co-founders, Mr. Steve Gorlin: CoRegen, Inc.,  MiMedx Group, Inc., a publicly-held biotechnology company (2007 – 2008) and SpineMedica, Corp., a subsidiary of MiMedx Group, Inc. (2005 – 2006); DARA BioSciences, Inc., a publicly-held biotechnology company (2002 – 2009), ClearPoint Neuro, a publicly-held company involved in MRI technology (1998 – 2010); GMP Companies, Inc., a private medical research company (1999 – 2001); EntreMed, Inc. a publicly-held biopharmaceutical research and development company (1991 – 1997); Medicis Pharmaceutical Corporation, a publicly-held dermatological company (1988 – 1991); Biopool International, Inc. (formerly CytRx Biopool, Ltd.), a publicly-held company engaged in the sale of pharmaceutical diagnostic test kits (1990 – 1991); and CytRx Corporation, a publicly-held pharmaceutical research and development company (1986 – 1989). Mr. Thomas has also served as the chief financial officer for several other start-up companies in other industries during the past ten years as the Chief Financial Officer including Motion Reality, Inc., a privately-held virtual reality company (2001 – present), and CorMatrix Cardiovascular, Inc., a privately held medical device company (2001 – 2018). Mr. Thomas is a certified public accountant.

Bryon Adinoff, MD

Lead Consultant Psychiatry

Dr. Bryon Adinoff is the Distinguished Professorship of Alcohol and Drug Abuse Research and a tenured Professor in the Department of Psychiatry at the University of Texas Southwestern Medical Center. He is also the Director of Research in Mental Health at the VA North Texas Health Care System. He received his medical degree from Michigan State University, completed residency training in psychiatry at Tulane University, and did a postdoctoral fellowship in the Laboratory of Clinical Studies at the National Institute on Alcohol Abuse and Alcoholism and is Board Certified in both Psychiatry and Addiction Psychiatry. Dr. Adinoff’s laboratory has conducted primarily human translational research, using a variety of pharmacological and behavioral probes to explore the brain and stress hormone disruptions that are associated with cocaine and alcohol use disorders and, more recently, addicted sunbed users. He has published over 160 articles and chapters on the biology and treatment of addiction and is Editor-in-Chief of The American Journal of Drug and Alcohol Abuse. Dr. Adinoff’s work has been funded by the Department of Veterans Affairs, the National Institutes on Drug Abuse, Alcohol Abuse and Alcoholism, and Arthritis and Musculoskeletal and Skin Diseases. He has been recognized as a Distinguished Fellow in the American Academy of Addiction Psychiatry and is a Fellow in the American College of Neuropsychopharmacology. Dr. Adinoff serves as Lead Psychiatry consultant for the Company.

Pascal J. Goldschmidt MD,

Director, Lead Consultant Cardiology

Pascal Goldschmidt MD is an accomplished physician (cardiologist), professor, healthcare leader, NIH-funded medical researcher and inventor. He has served as a Tenured Professor at three prestigious institutions, Duke University School of Medicine, Ohio State University (OSU) and University of Miami. He was Center Director at Johns Hopkins University School of Medicine (then OSU), Chief of Cardiology at OSU, and Chairman of Medicine at Duke. In 2006, he became Dean of the Miller School of Medicine and Founder/CEO of UHealth, the University of Miami Health System (2006- 2016). Dr. Goldschmidt received the inaugural Jay and Jeanie Schottenstein Prize in Cardiovascular Sciences from the Ohio State University Heart and Vascular Center. The prize, the largest for cardiovascular disease, is awarded biennially to an international leader in the clinical sciences of cardiovascular medicine. He is currently the President and Chairman, ALZADY INTERNATIONAL, LLC. Dr. Goldschmidt serves as Lead Cardiology consultant for the Company and an active member of our Board of Directors.

Meet the Board of Directors

Meet the group of people responsible for steering and shaping the future of our organization.

Christopher Hassan

Chris is a Senior Healthcare Executive with over 25 years of experience in healthcare including drug development, pharmaceutical operations and as an addiction service provider. Chris was the founder and CEO of Symetria Health from 2016-2020 pioneering comprehensive OUD treatment in comorbid patients. He completed the first retrospective national analysis of all OUD patients at the claims level documenting Symetria’s superior outcomes and cost savings to payers resulting in enhanced reimbursement at more than 3x average rates. While with Reckitt Beckiser, Richmond, VA, Chris was a founder and pioneer leading the introduction of Suboxone into the US Market creating the office-based treatment model for opioid dependence. He created alliances with Addiction Medicine organizations and government agencies including the American Society of Addiction Medicine (ASAM) and American Academy of Addiction Psychiatry (AAAP) and the American Osteopathic Association of Addiction Medicine (AOAAM) for the development of buprenorphine training and education requirements for the DEA waiver requirements. Subsequently, he served as the Chief Executive Officer and President of Colonial Management Group- the largest provider of methadone services of opioid addiction treatment centers in the US, at that time. Chris sits on several boards while also developing patented opioid product combinations focused on preventing diversion and inadvertent benzodiazepine overdose in patients.

Amb. Hans Hertell

Hans joined the Board in 2017. Ambassador Hertell has over 30 years’ experience in government, public affairs, business, and banking. He was sworn in as the United States Ambassador to the Dominican Republic on November 8, 2001. Ambassador Hertell has served with distinction as an officer and member of the board of directors of public and private corporations. From 1989 to 1991, he served on the Board of Directors of the Federal Home Loan Bank of New York, as a Public Interest director, a banking system created by U.S. Congress which at the time had over 1.3 trillion dollars in assets. Subsequently, Ambassador Hertell served as Chief Executive Officer and Chairman of the Board of Ponce Federal Bank (NYSE), one of the largest publicly traded corporations in the Caribbean, with $1.3 billion in assets at the time. He also served on the Board of Directors of OCASO Insurance, a subsidiary of one of the largest insurance and reinsurance holding companies in Spain. Ambassador Hertell currently serves on the Board of Directors of InterEnergy Holdings, a holding company that owns and operates power generation and distribution assets in Latin America and the Caribbean and is a member of the International Advisory Board of Brasilinvest Group, headquartered in Sao Paulo, Brazil.

Heather Callander-Potters, MBA

Ms. Heather Callender-Potters serves as the Vice Chair & Chief Business Development Officer at PharmaJet, Inc., a company she co-founded, which is focused on immunization utilizing a needle-free approach. Ms. Potters began her private equity career in 1991, where she served as a partner and Vice President of Enterprise Investors. Expanding to investment oversight for the Central & Eastern European and CIS countries, she subsequently served as a Partner of BPEP International Limited, and Managing Partner of Barings Communications Equity Limited, co-sponsored by CEA Capital Advisors, LLC. Her investment background includes all aspects of direct investment and portfolio management including privatization, strategic partner search, direct investment with local entrepreneurs, licensing of intellectual property and other assets, and private and public offerings. She has held many board and advisory positions over time, in public and private companies, operating in a variety of countries, with concentrations primarily in tech and health focused companies, including PharmaJet, ComputerLand, Sygnity, Consolidated Communications Corporation, PenneCom, Cerescan, Curemark, Encryptics, and NFT. She holds an M.B.A. from The Wharton School and a B.A. in International Management from Claremont Mckenna College.

Guy Bolton

Guy joined the Board in February 2020. Mr. Bolton brings to DemeRx over 25 years’ experience in business, specifically in drug development, project management and healthcare technology. He currently serves as President of North America Bolton Equities (BE), a private equity company. He has held various leadership positions at established businesses including Pharmaceutical companies with senior management and director experience across drug development, project/study management, and operations. Previously, Guy was Associate Vice President from 2015 to 2018 and the head of US Clinical operations from 2012 to 2018 at Ferring Pharmaceuticals. Guy brings knowledge to virtually every aspect of early to late stage drug development with Extensive US and Global development experience and expertise in Clinical Operations, Project Management, Due Diligence, Compliance and Quality Assurance. He served on the board of Transaction Services Group from 2015 until 2019. He currently sits on investee boards where he is advancing various healthcare technologies. These activities give him significant exposure to business governance and trends. Guy also serves on the investment committee of Bolton Equities.